Receptor Autoradiography

Receptor Autoradiography

Autoradiography can be used to determine anatomical distribution of binding sites of a radiolabeled drug (receptor distribution), receptor occupancy of a competing unlabeled drug given either in vitro or ex vivo & biodistribution of radiolabeled drug among the organs.

Autoradiography can be used to determine in tissue sections

Receptor Occupancy Autoradiography

Receptor occupancy determinations of a competing unlabeled drug given either in vitro, in vivo orex vivo.

Quantitative Whole Body Autoradiography

in vivo ADME studies are an important component of the drug development process which is designed to investigate the Absorption, Distribution, Metabolism, and Excretion (ADME) of your novel compounds.

in vitro Receptor Distribution Autoradiography

in vitro Anatomical distribution (receptor distribution) of binding sites of a radiolabeled or non-radiolabeled drug.

Functional Autoradiography [35S]-GTPγS

[35S]-GTPγS autoradiography reveals distribution and functional activation of GPCR receptors.

Case Studies