The most logical way to study the interaction between your specific molecule and the target receptor is to use a RADIO-labelled version. METIS Labs’ can provide you custom radiolabeling and custom radiosynthesis of your small molecules, peptides, antibodies and proteins.
High specific activity and retention of the molecular structure is essential for the success of radiometric assays such as
in vitro Autoradiography
ex vivo Autoradiography
in vivo receptor occupancy
Analysis of products is performed using methods including LC-MS, HPLC-Radiochemical Flow, HPLC-UV, TLC Radioscan and NMR.
Custom synthesis is an important part of our business. Often we subsidize the cost of custom synthesis for potentially new catalog products. Many of our exclusive products in our radiochemical catalog have been derived from custom syntheses. Built upon years of experience in a top pharmaceutical company our organic chemists provide world class expertise and integrated solutions to accelerate your drug development programs.