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Antibody (Ab) Homologous Competition (BMAX & KD)

Antibody (Ab) Homologous Competition (BMAX & KD)

A homologous competition is a concentration response curve with an unlabeled compound that is identical to the radioligand being used. Radioligand concentration is constant in the experiment. Homologous competition experiments can be used as an alternative to saturation experiments to determine receptor affinity (Kd) and density (Bmax). When using [125I]-ligands, a non-radioactive iodo-ligand should be used if possible.

Antibody Homologos Competition Binding Data GraphPad

Antibody Homologos Competition Binding Data GraphPad

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Compound Characterization

Compound Characterization

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

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Compound Characterization 1

Compound Characterization 1

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

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