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Receptor Autoradiography

Receptor Autoradiography

Autoradiography can be used to determine anatomical distribution of binding sites of a radiolabeled drug (receptor distribution), receptor occupancy of a competing unlabeled drug given either in vitro or ex vivo & biodistribution of radiolabeled drug among the organs.

Autoradiography can be used to determine in tissue sections

Case Studies

Compound Characterization

Compound Characterization

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

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Compound Characterization 1

Compound Characterization 1

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

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