888-295-7550 info@metislabs.com
services / Functional Assays / Functional Binding Assay 96-Well Plate

Functional Binding Assay 96-Well Plate

Functional Binding Assay 96-Well Plate

[35S]-GTPγS binding, also known as a GTP exchange assay, is a powerful method used to measure the activation of G protein-coupled receptors (GPCRs) by a ligand.

[35S]-GTPγS binding can be used to:

  • Created by potrace 1.10, written by Peter Selinger 2001-2011 Determine if a ligand can activate a GPCR of interest
  • Created by potrace 1.10, written by Peter Selinger 2001-2011 Single concentration screening or dose-response to determine pharmacological values of potency (EC50) & efficacy (EMAX)
  • Created by potrace 1.10, written by Peter Selinger 2001-2011 Determine full, partial, or inverse agonist and antagonist activity

How We Work

Brainstorming

1

Research

2

Report

3

Case Studies

Compound Characterization

Compound Characterization

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

View More
Compound Characterization 1

Compound Characterization 1

Compound Characterization Study Goal Determine ex vivo receptor occupancy of CMPDx at Orexin-1 (OX1) receptors using radiolabeled Orexin antagonist Created by potrace 1.10, written by Peter Selinger 2

View More

Call Us On

888-295-7550